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Publications

Platelets

Goel MS, Diamond SL. Factor VIIa-mediated tenase function on activated platelets under flow. J Thromb Haemost. 2004 Aug;2(8):1402-10. PMID: 15304047 [pdf]

Brass LF, Jiang H, Wu J, Stalker TJ, Zhu L. Contact-dependent signaling events that promote thrombus formation.
Blood Cells Mol Dis. 2006 Mar-Apr;36(2):157-61. Epub 2006 Feb 13. PMID: 16473534 [pdf]

Brass LF, Zhu L, Stalker TJ. Minding the gaps to promote thrombus growth and stability. J Clin Invest. 2005 Dec;115(12):3385-92. Review. PMID: 16322784 [pdf]

Prevost N, Woulfe DS, Jiang H, Stalker TJ, Marchese P, Ruggeri ZM, Brass LF. Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9820-5. Epub 2005 Jul 1. PMID: 15994237 [pdf]

Prevost N, Woulfe D, Tanaka T, Brass LF. Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9219-24. Epub 2002 Jun 25. PMID: 12084815 [pdf]

Molino M, Bainton DF, Hoxie JA, Coughlin SR, Brass LF. Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation. J Biol Chem. 1997 Feb 28;272(9):6011-7. PMID: 9038223 [pdf]

Coagulation

Okorie UM, Diamond SL. Matrix Protein Microarrays for Spatially and Compositionally Controlled Microspot Thrombosis under Laminar Flow. Biophys J. 2006 Nov 1;91(9):3474-81. Epub 2006 Aug 11. PMID: 16905604 [pdf]

Gosalia DN, Denney WS, Salisbury CM, Ellman JA, Diamond SL. Functional phenotyping of human plasma using a 361-fluorogenic substrate biosensing microarray. Biotechnol Bioeng. 2006 Aug 20;94(6):1099-110. PMID: 16575920 [pdf]

Lo K, Denney WS, Diamond SL. Stochastic modeling of blood coagulation initiation. Pathophysiol Haemost Thromb. 2005;34(2-3):80-90. PMID: 16432310 [pdf]

Gosalia DN, Salisbury CM, Maly DJ, Ellman JA, Diamond SL. Profiling serine protease substrate specificity with solution phase fluorogenic peptide microarrays. Proteomics. 2005 Apr;5(5):1292-8. PMID: 15742319 [pdf]

Gosalia DN, Salisbury CM, Ellman JA, Diamond SL. High throughput substrate specificity profiling of serine and cysteine proteases using solution-phase fluorogenic peptide microarrays. Mol Cell Proteomics. 2005 May;4(5):626-36. Epub 2005 Feb 10. PMID: 15705970 [pdf]

Lo K, Diamond SL. Blood coagulation kinetics: high throughput method for real-time reaction monitoring. Thromb Haemost. 2004 Oct;92(4):874-82. PMID: 15467920

Fibrinolysis

 

Hemodynamics: Aggregation and Adhesion

Edmondson KE, Denney WS, Diamond SL. Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime. Biophys J. 2005 Nov;89(5):3603-14. Epub 2005 Aug 12. PMID: 16100264 [pdf]

in vivo

Woulfe D, Jiang H, Morgans A, Monks R, Birnbaum M, Brass LF. Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2. J Clin Invest. 2004 Feb;113(3):441-50. PMID: 14755341[pdf]

 

 
Brass
Diamond
Hammer
King
Biros
Sinno
    Institute for Medicine & Engineering (IME)
    3340 Smith Walk
    1020 Vagelos Research Laboratories
    University of Pennsylvania
    Philadelphia, PA 19104-6383
    Phone; 215-573-5702
    Fax: (215) 573-7227